Normal Breast-Cancer Gene Keeps Cancer at Bay by Blocking DNA Replication

The protein encoded by the tumour-suppressor gene BRCA1 may keep breast and ovarian cancer in check by preventing transcription of repetitive DNA sequences, says a study published today in Nature . This explanation brings together many disparate theories about how the gene functions and could also shed light on how other tumour suppressors work

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Normal Breast-Cancer Gene Keeps Cancer at Bay by Blocking DNA Replication