Gene-Therapy Successes Spur Hope for Embattled Field

From Nature magazine. When it was first used in the 1990s to treat an immune deficiency, gene therapy — treating diseases by correcting a patient’s faulty genes — was touted as a breakthrough that was likely to cure scores of hereditary diseases. But when 18-year-old Jessie Gelsinger died in 1999 after having a corrected gene injected to treat his liver disease, the field became wary, and researchers found it difficult to fix the problems associated with the technique

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Gene-Therapy Successes Spur Hope for Embattled Field