CAUGHT TOO EARLY In discussing the search for better detection of breast cancer in “ Beyond Mammograms ,” Nancy Shute misses one key problem: when tests become too “perfect.” As we have learned from our experience in detecting prostate cancer by testing for high levels of the prostate-specific antigen protein, finding cancers at extraordinarily early stages raises new issues. Are we now left to treat cancers that have no clinical relevance? We already often diagnose breast cancers at one to three millimeters in size.
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