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Mitochondrial network of an endothelial cell is shown in green Research projects evolve in a fortuitous manner, often guided by a convergence of novel observations, intuition, helpful colleagues and unique personal circumstances. It is precisely this constellation that prompted two cardiologists to study the mitochondrial networks in lung cancer cells.

Arriving on the heels of Constellation Audio’s $345,000 cost-is-no-object Reference system—which launched in stages last year and pushes the limits of high fidelity—comes the Southern California manufacturer’s more “modestly priced” Performance Series. By simplifying and automating its manufacturing and assembly processes, and using fewer exotic parts, Constellation succeeds in creating ...

Serial entrepreneur Glen Blickenstaff says his retirement goal of living on a boat is the benchmark to which he measures all his business decisions. “Basically I’m on my way to Australia.” That was a line delivered by James Garner in the 1969 movie Support your Local Sheriff! He was handy with a six shooter and basically an entrepreneur, well a drafted entrepreneur

By Alison Abbott of Nature magazine The health-research division of the European Commission launches its largest-ever project next week with a €30-million (US$41-million) investment in understanding the human epigenome, the constellation of DNA modifications that shape how genes are expressed. With the project, called BLUEPRINT, Europe intends to become a major player in the International Human Epigenome Consortium (IHEC), set up last year to help biologists understand how the epigenome influences health and disease

[youtube aPgPyq8EonE] NASA is, the Agency urges in a news release , "ready to move forward with the development of the Space Launch System--an advanced heavy-lift launch vehicle that will provide an entirely new national capability for human exploration beyond Earth's orbit. The messy politics behind the story aren't innovative (the Apollo program was canceled to make way for the Shuttle, and the Shuttle has now been ditched to make way for the SLS, with bitter discussions and budget controversies along for the ride, as ever) but the rocket itself is going to be. Because NASA's next "big stick" binds together 50 years of research and lessons into one 21st century rocket

NASA's revealed plans for manned human spaceflight, centering on the four-seat, conical Orion capsule. NASA's plans for manned human spaceflight are salvaged from the wreckage of the Constellation program

By Adam Mann of Nature magazine NASA should be revitalized "not just with dollars, but with clear aims and a larger purpose," US President Barack Obama said last April, after cancelling the previous administration's under-resourced Constellation programme of rockets and capsules for human space flight. [More]