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Angry Birds, the incredibly popular game, was software maker Rovio’s 52nd attempt. They spent eight years and nearly went bankrupt before finally creating their massive hit. Pinterest is one of the fastest-growing websites in history, but struggled for a long time.

By Arron Frood of Nature magazine Has a cheap and effective treatment for chronic pain been lying under clinicians' noses for decades? Researchers have found that a very high dose of an opiate drug that uses the same painkilling pathways as morphine can reset the nerve signals associated with continuous pain--at least in rats. If confirmed in humans, the procedure could reduce or eliminate the months or years that millions of patients spend on pain-managing prescription drugs

In the past 15 months several devastating earthquakes have rumbled beneath the Pacific.

In the past 15 months several devastating earthquakes have rumbled beneath the Pacific. In February 2010 a magnitude 8.8 temblor slammed central Chile; this past September a magnitude 7 quake walloped Christchurch, New Zealand, leading to a magnitude 6.3 aftershock this past February.