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Geneticist Oliver Smithies is a toolmaker. He shared the Nobel Prize in Physiology or Medicine in 2007 for discoveries that led to the development of knockout mice

Oliver Smithies won the Nobel Prize in physiology or medicine in 2007. On June 27th, he spoke to students [at the Lindau Nobel Laureate Meeting] about what he learned from his thesis research, which involved developing a new method to measure the osmotic pressures of mixes of proteins: "Here's my osmotic pressure measurement. And I was rather proud of this method