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Early research on the sharpest octogenarians reveals unusually youthful brain regions A nasty affliction sets into humans as they advance in years. The hair either disappears or thins into a fuzzy halo, the skin sags and bunches, while inside the brain, changes set in that slow our reaction times and cause our memories to fade. A steady, widespread thinning out of the brain s cortex, the outermost layer of the brain, is thought to underlie some of this cognitive transformation

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