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Your genetic tolerance for risk, coupled with new productivity gains through smart technology, can help your company revolutionize its industry. Mankind's most innovative , large-scale achievements: building the Pyramids of Egypt and the Panama Canal—even putting a man on the moon—were each accomplished with roughly the same number of people: 100,000. Luis von Ahn, the Carnegie Mellon professor who researched these epic projects, makes the observation that 100,000 may well be the practical limit on the number people it was possible to organize, using pre-Internet technology.

Learn from these entrepreneurs that ditched the office to cut overhead expenses, be closer to family, and enjoy, as one entrepreneur put it, the "10-step commute." Thinking of starting up —but don’t want the daily trek to an office? Home-based businesses, or virtual businesses, provide plenty of advantages, especially if you’re looking to bootstrap your operation. Here’s a look at 11 entrepreneurs that ditched the office to cut overhead expenses, be closer to family, and enjoy, as one entrepreneur put it, the “10-step commute.” Green and Profitable Shel Horowitz Shel Horowitz started his first home-based business in 1981 on the kitchen table of a rental apartment.

The lead plaintiff in the Supreme Court case against Obama's health care act filed for bankruptcy. That raises some thorny legal questions about the future of the case. Mary Brown became the face of the anti-Obamacare movement last year, as she and Kaj Ahlburg became the lead plaintiffs in a lawsuit to stop the administration's healthcare overhaul.

Mark and Glenda Dodd of Panama City Beach, Florida, could have booked a Mexico-bound cruise out of Miami, but on Monday they stood among hundreds of other passengers lining up to board the Carnival Cruise Line ship Elation in New Orleans.

New renovations will let even "Post-Panamax" ships cross the isthmus, altering the economics of global shipping to the advantage of countries that produce cheap goods for the developed world. What a difference a century makes.

Gary Hoover is an entrepreneur, writer, speaker and educator. He is the founder of BOOKSTOP and Hoovers, Inc. Below, Gary explains why he believes that Mexico is vital to the future of the U.S.

The death of large predators isn't just a tragedy, it can lead to the utter destruction of whole ecosystems--something that is already happening in many parts of the world. You may not have noticed, but we are in the early to middle stages of the Earth's sixth large extinction event. Compared to the

By Sean Mattson CERRO SAPO, Panama (Reuters) - The harlequin frog that hops and swims the rocky streams of a damp niche of Toad Mountain in eastern Panama's dense tropical jungle has probably been on Earth for around 3 million years.