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Sirtuin Protein Linked to Longevity in Mammals for First Time

By Heidi Ledford of Nature magazine At last, a member of the celebrated sirtuin family of proteins has been shown to extend lifespan in mammals -- although it's not the one that has received the most attention and financial investment. Sirtuin genes and the proteins they encode have intrigued many researchers who study ageing ever since they were first linked to longevity in yeast.

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