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Video: Encouraging results from new cancer treatment

A clinical trial of a drug treating advanced stages of breast and ovarian cancers is showing promising results. The drug targets cancer cells without the effects of chemotherapy

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Drug shortage slows clinical trials

By Heidi Ledford of Nature magazine Potential cancer treatments are loitering in the wings as clinical trials are delayed by widespread shortages of common chemotherapy drugs. The I-SPY 2 Breast Cancer Clinical Trial, for example, a high-profile experiment aiming to test the use of certain molecular markers to guide cancer treatment, was designed to allow researchers to adapt the study's protocol in response to early results. [More]

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Vaccine Trial’s Ethics Criticized

By Priya Shetty of Nature magazine A clinical trial that came under fire in India threatens to have a dual legacy: inflaming unfounded fears about a lifesaving vaccine and raising new questions about the management of medical research in the country. [More]

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Fast Track to Vaccines: How Systems Biology Speeds Drug Development (preview)

Aids researchers and advocates were devastated in 2007, when a much anticipated vaccine against HIV unexpectedly failed to protect anyone in a clinical trial of 3,000 people. Even worse, the experimental inoculation, developed with money from the Merck pharmaceutical company and the National Institute of Allergy and Infectious Diseases, actually increased the chances that some people would later acquire HIV

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