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By Declan Butler and Heidi Ledford of Nature magazine The U.S.

By Heidi Ledford of Nature of magazine With sales of more than $100 billion since it was introduced in 1997, the cholesterol-lowering drug Lipitor (atorvastatin) is an unparalleled pharmaceutical superstar.

By Heidi Ledford of Nature magazine It would not be the first psychiatric drug to run aground in a large study after sailing through early trials. [More]

By Heidi Ledford of Nature magazine A computer program has been trained to grade breast cancer, predicting which tumours are associated with worse outcomes and, therefore, deserve more aggressive treatment.

By Heidi Ledford of Nature magazine Two weeks after receiving an experimental treatment for his cancer, David Porter's 65-year-old leukemia patient seemed to take a turn for the worse. [More]

By Heidi Ledford of Nature magazine Early next year, a drug for cystic fibrosis is expected to come before the US Food and Drug Administration for approval. [More]

By Heidi Ledford of Nature magazine When stem-cell clinics are asked for documentation about the treatments they offer, some are quick to produce letters from lawyers instead. [More]

By Heidi Ledford of Nature magazine When pharmaceutical company Pfizer announced on June 8 that it is teaming up with eight research institutions in the Boston area to hunt for candidate drugs, the news was cheered from all sides. [More]

By Heidi Ledford For more than 50 years, the autoimmune disease lupus has confounded drug developers.