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James Locke, a flight surgeon at NASA's Johnson Space Center in Houston, has made dozens of people sick in the name of science. When he puts subjects in a spinning chair designed to induce motion sickness, roughly 70 percent of them succumb--and at nearly the exact same point on each ride. Locke has used this research and his work with shuttle astronauts to determine which medications and doses best prevent the nausea and vomiting associated with motion sickness

"The orbiter is a completely different vehicle than anything that has ever flown in space." It was a work platform, a spacewalk platform, a construction site with a robotic arm, a laboratory, a people mover. It was a complex vehicle operating at the edge of its performance, with very little margin for error," John Shannon, program manager at the Johnson Space Center in Houston told Air & Space magazine in March.