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This year has been a painful one for fans of the NFL's Indianapolis Colts, the perennial contender that has fallen to 0–10 on the season . Perhaps Hoosiers can take some small comfort in the thought of a world where star quarterback Peyton Manning is healthy rather than hobbled and the Colts are undefeated rather than winless. If the cosmological concept of the multiverse is correct , such a world could exist right now.

Editor's note: In the August issue of Scientific American, cosmologist George Ellis describes why he's skeptical about the concept of parallel universes. Here, multiverse proponent multiverse proponents Alexander Vilenkin and Max Tegmark offer counterpoints, explaining why the multiverse would account for so many features of our universe--and how it might be tested.