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Now that everyone is a so-called entrepreneur, the word is losing its edge. And entrepreneurship with a big E is a pain in the neck. We are in the golden age of entrepreneurship.

Is it time to take the leap? Here are founders' words of wisdom on whether you're truly ready to make it on your own. I'll never forget pressing the "send" button on the e-mail to my boss letting him know that I was leaving to start a company

The Killer Bacteria Hall of Fame no doubt houses the usual suspects: Yersinia pestis , perpetrator of the Plague; Treponema pallidum, the spiral-shaped culprit in syphilis ; and Vibrio cholerae , the swimmer that causes cholera .