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Many membrane proteins serve as gateways in and out of the cell. Because they act as “traffic control” for infectious agents and disease-fighting drugs, they are the targets of more than 60 percent of all drugs on the market. Yet of the estimated 30,000 membrane proteins in the human body, scientists understand the detailed structures of only 18.

DURBAN, South Africa--Former entomologist Diarmid Campbell-Lendrum of the World Health Organization worries about nosebleeds more than the average person. That's because he's one of the estimated 12 million people worldwide afflicted with leishmaniasis --a potentially fatal parasitic disease characterized most often by lesions on the skin and/or mucus membranes--caused by the bite of a sandfly. [More]