Twisting molecules by brute force: A top-down approach

Molecules that are twisted are ubiquitous in nature, and have important consequences in biology, chemistry, physics and medicine. Some molecules have unique and technologically useful optical properties; the medicinal properties of drugs depend on the direction of the twist; and within us – think of the double helix – twisted DNA can interact with different proteins.

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Twisting molecules by brute force: A top-down approach