Fearless Youth: Prozac Extinguishes Anxiety by Rejuvenating the Brain

Once adult lab mice learn to associate a particular stimulus–a sound, a flash of light–with the pain of an electric shock, they don't easily forget it, even when researchers stop the shocks. But a new study in the December 23 issue of Science shows that the antidepressant Prozac (fluoxetine) gives mice the youthful brain plasticity they need to learn that a once-threatening stimulus is now benign.

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Fearless Youth: Prozac Extinguishes Anxiety by Rejuvenating the Brain